BDBM50547274 CHEMBL4743066

SMILES C=CC(=O)Nc1cccc(c1)-c1c[nH]c2ncnc(Nc3ccc(OC(c4ccccc4)c4ccccc4)cc3)c12

InChI Key InChIKey=MJWAOOZOZOALNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50547274   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547274BDBM50547274(CHEMBL4743066)
Affinity DataIC50: 26nMAssay Description:Inhibition of C-terminal His6-tagged HER2 (703 to 1029 residues) (unknown origin) expressed in Sf9 insect cells using TK as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed