BDBM50547279 CHEMBL4783667

SMILES OCCOc1ccc(cc1NC(=O)C=C)-c1c[nH]c2ncnc(Nc3ccc(CN4C(=O)c5ccccc5C4=O)cc3)c12

InChI Key InChIKey=LDZCMFQTVWKVEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50547279   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50547279(CHEMBL4783667)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal His6-tagged HER2 (703 to 1029 residues) (unknown origin) expressed in Sf9 insect cells using TK as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed