BDBM50547698 CHEMBL4761909

SMILES COc1cc(/C=C(/C(N)=O)n2c3ccccc3c3c4c(c5c6ccccc6[nH]c5c32)CNC4=O)ccc1O

InChI Key InChIKey=XQJNRKJYIPJJPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547698   

TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547698BDBM50547698(CHEMBL4761909)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of N-terminal His10-StrepII tagged human ROCK2 catalytic domain (1 to 553 residues) expressed in Sf9 insect cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547698BDBM50547698(CHEMBL4761909)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PKCtheta (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed