BDBM50547730 CHEMBL4796257

SMILES C[C@@H]1O[C@H](C[C@@H](N)[C@H]1OC(O)C1CO1)n1c2ccccc2c2c3C(=O)NCc3c3c4ccccc4[nH]c3c12

InChI Key InChIKey=OUQHIYLYXNEVEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547730   

TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50547730(CHEMBL4796257)
Affinity DataIC50: 140nMAssay Description:Inhibition of N-terminal His10-StrepII tagged human ROCK2 catalytic domain (1 to 553 residues) expressed in Sf9 insect cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50547730(CHEMBL4796257)
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of PKCtheta (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed