BDBM50547752 CHEMBL4797113

SMILES CC1CCN(CC1c1cc(nc2ncnn12)C(F)F)C(=O)c1ccc2occc2c1

InChI Key InChIKey=LYEXNMDIPNPRIQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50547752   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547752(CHEMBL4797113)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE4D3 expressed in Sf9 cells by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50547752(CHEMBL4797113)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE1B1 expressed in HEK cells by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547752(CHEMBL4797113)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE11A4 expressed in HEK cells by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547752(CHEMBL4797113)
Affinity DataIC50:  2.24E+3nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547752(CHEMBL4797113)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE7A1 expressed in Sf9 cells by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547752(CHEMBL4797113)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed