BDBM50547752 CHEMBL4797113
SMILES CC1CCN(CC1c1cc(nc2ncnn12)C(F)F)C(=O)c1ccc2occc2c1
InChI Key InChIKey=LYEXNMDIPNPRIQ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50547752
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE4D3 expressed in Sf9 cells by scintillation counting methodMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Human)
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE1B1 expressed in HEK cells by scintillation counting methodMore data for this Ligand-Target Pair
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE11A4 expressed in HEK cells by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE7A1 expressed in Sf9 cells by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair