BDBM50547993 CHEMBL4795757
SMILES Cc1ncc(cn1)-c1ccn2ncc(-c3ccc4NC(=O)[C@@](C)(CC5CC5)c4c3)c2n1
InChI Key InChIKey=BWZJQTMIXIJENC-DEOSSOPVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50547993
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-induced AKT phosphorylation at Ser473 residue preincubated for 20 mins...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal His6 tagged recombinant full-length human PI3Kdelta/human recombinant full-length p85alpha expressed in baculovirus infected...More data for this Ligand-Target Pair