BDBM50548033 CHEMBL4743670

SMILES CCN(CC)S(=O)(=O)c1ccc(cc1)[C@H]1C[C@@H]1NCc1ccccc1

InChI Key InChIKey=PBSVFESALQWDIE-UXHICEINSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50548033   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50548033(CHEMBL4743670)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant LSD1 using ARTK(diMe)QTARKSTGGKAPRKQLA as substrate incubated for 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50548033(CHEMBL4743670)
Affinity DataIC50:  29nMAssay Description:Inhibition of human LSD1 expressed in Escherichia coli BL21 (DE3) cells using (ARTK(diMe)QTARKSTGGKAPRKQLA peptide as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50548033(CHEMBL4743670)
Affinity DataIC50:  526nMAssay Description:Inhibition of MAO-A (unknown origin) preincubated for 20 mins using 5-hydroxytryptamine as substrate followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50548033(CHEMBL4743670)
Affinity DataIC50:  29nMAssay Description:Inhibition of LSD1 (unknown origin) incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50548033(CHEMBL4743670)
Affinity DataIC50:  29nMAssay Description:Inhibition of KDM1A (unknown origin) incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50548033(CHEMBL4743670)
Affinity DataIC50:  526nMAssay Description:Inhibition of recombinant MAO-A (unknown origin) using 5-hydroxytryptamine as substrate incubated for 20 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50548033(CHEMBL4743670)
Affinity DataIC50:  702nMAssay Description:Inhibition of recombinant MAO-B (unknown origin) using benzylamine as substrate incubated for 20 mins followed by substrate addition measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50548033(CHEMBL4743670)
Affinity DataIC50:  702nMAssay Description:Inhibition of MAO-B (unknown origin) using benzylamine as substrate preincubated for 20 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed