BDBM50548052 CHEMBL3814568

SMILES COc1cc(ccc1-c1cnc(C)o1)-c1nnc2n1CCC[C@@]2(Oc1cc(F)c(F)c(F)c1)C(C)(C)O

InChI Key InChIKey=TYZSJCRDLQKNAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50548052   

TargetPresenilin-1(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50548052(CHEMBL3814568)
Affinity DataIC50: 1.00E+4nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed