BDBM50548054 CHEMBL3813841

SMILES COc1cc(ccc1-c1cnc(C)o1)-c1nnc2n1CCCC21OCc2c(cccc2C(F)(F)F)N(CC(F)(F)F)C1=O

InChI Key InChIKey=HCGIRXDLCPUVSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50548054   

TargetPresenilin-1(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50548054(CHEMBL3813841)
Affinity DataIC50: 31nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed