BDBM50548056 CHEMBL3814348

SMILES COc1cc(ccc1-c1cnc(C)o1)-c1nnc2n1CCCC2(Oc1ccc(F)c(Cl)c1)C(C)(C)O

InChI Key InChIKey=IBXFWTUJQZVKBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50548056   

TargetPresenilin-1(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50548056(CHEMBL3814348)
Affinity DataIC50: 38nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed