BDBM50548058 CHEMBL3618213

SMILES COc1cc(ccc1-c1cnc(C)o1)-c1nnc2C(CCCn12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=LWCVAPYVEVTRGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50548058   

TargetPresenilin-1(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50548058(CHEMBL3618213)
Affinity DataIC50: 240nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as reduction in amyloid beta42 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed