BDBM50548060 CHEMBL4762609

SMILES Fc1ccc(CC(=O)N2CCC(CC2)Nc2ncc3c(n[nH]c3n2)N2CCOCC2)cc1F

InChI Key InChIKey=XPYOCUNKDACBLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548060   

TargetMitogen-activated protein kinase 15(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50548060(CHEMBL4762609)
Affinity DataIC50: 110nMAssay Description:Inhibition of human ERK8 (2 to 544 residues) incubated for 5 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50548060(CHEMBL4762609)
Affinity DataIC50: 550nMAssay Description:Inhibition of human p38beta MAPK (1 to 364 residues) incubated for 5 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed