BDBM50548288 CHEMBL4743953

SMILES CO[C@@]12CC[C@H](NCCCC(=O)O)[C@@H]3Oc4c(O)ccc5c4[C@@]31CCN(C)[C@@H]2C5

InChI Key InChIKey=HAVQMMOFQDNJHT-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50548288   

TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548288BDBM50548288(CHEMBL4743953)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548288BDBM50548288(CHEMBL4743953)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548288BDBM50548288(CHEMBL4743953)
Affinity DataKi:  13nMAssay Description:Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548288BDBM50548288(CHEMBL4743953)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548288BDBM50548288(CHEMBL4743953)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]U69,593 from kappa opioid receptor in guinea-pig brain membranes incubated for 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50548288BDBM50548288(CHEMBL4743953)
Affinity DataEC50:  2.03E+3nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed