BDBM50548353 CHEMBL4762290

SMILES CNC(=O)c1nn(C)c2c(C)cc(Nc3nccc(n3)-n3cc(CN(C)C)cn3)cc12

InChI Key InChIKey=IQOIYVOYKZHJJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548353   

LigandPNGBDBM50548353(CHEMBL4762290)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human ERG by plate-based planar patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50548353(CHEMBL4762290)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of recombinant full length SYK (unknown origin) by biochemical Omnia assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed