BDBM50548356 CHEMBL4792651

SMILES CNC(=O)c1nc(C)n2ccc(Nc3nccc(n3)-n3cc(cn3)[C@@H]3C[C@@H](F)CN3C)cc12

InChI Key InChIKey=MSNZEHCCRXNMBZ-WBVHZDCISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548356   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50548356(CHEMBL4792651)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human ERG by plate-based planar patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50548356(CHEMBL4792651)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant full length SYK (unknown origin) by biochemical Omnia assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed