BDBM50549336 CHEMBL4785146
SMILES COc1ccc(NC(=O)Nc2cnc3ccc(cc3c2N(C)C2CCOCC2)C#N)cc1Cl
InChI Key InChIKey=HFKNLMRGBDXLEB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50549336
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Allosteric inhibition of human wild-type full-length MALT1 (329 to 824 residues) protease activity using Ac-Leu-Arg-Ser-Arg Rh110-dPro as substrate p...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Allosteric inhibition of MALT1 in human OCI-LY3 cells assessed as reduction in BCL10 cleavage measured after 24 hrs by ELISAMore data for this Ligand-Target Pair