BDBM50549418 CHEMBL4758019

SMILES C#Cc1cccc(Nc2cc(C)nc3nc(SCc4nc5ccccc5[nH]4)nn23)c1

InChI Key InChIKey=FTLWKGLSMVVVBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549418   

TargetATP-dependent translocase ABCB1(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549418BDBM50549418(CHEMBL4758019)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of ABCB1 in multidrug-resistant human SW620/Ad300 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed