BDBM50549555 CHEMBL4747321

SMILES Oc1ccc(\C=C\C(=O)NNC(=O)COc2cccnc2)cc1O

InChI Key InChIKey=ZOFDQTHDCXJKRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549555   

TargetProstaglandin G/H synthase 2(Human)
University of Mysore

Curated by ChEMBL
LigandPNGBDBM50549555(CHEMBL4747321)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of COX-2 (unknown origin) assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Mysore

Curated by ChEMBL
LigandPNGBDBM50549555(CHEMBL4747321)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibition of COX-1 (unknown origin) assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed