BDBM50549557 CHEMBL4763455

SMILES Oc1ccc(\C=C\C(=O)NNC(=O)COc2ccc(Br)cc2)cc1O

InChI Key InChIKey=GKXAVMITOMWEIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549557   

TargetProstaglandin G/H synthase 2(Human)
University of Mysore

Curated by ChEMBL
LigandPNGBDBM50549557(CHEMBL4763455)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of COX-2 (unknown origin) assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Mysore

Curated by ChEMBL
LigandPNGBDBM50549557(CHEMBL4763455)
Affinity DataIC50: 2.33E+5nMAssay Description:Inhibition of COX-1 (unknown origin) assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed