BDBM50550660 CHEMBL4783324
SMILES FC1(F)CCN(CCOc2ccc3Sc4c(Cc3c2)cccc4-c2cc(=O)cc(o2)N2CCOCC2)CC1
InChI Key InChIKey=ZPTWTJJPTQLASI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50550660
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Chdi Management/Chdi Foundation
Curated by ChEMBL
Chdi Management/Chdi Foundation
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Chdi Management/Chdi Foundation
Curated by ChEMBL
Chdi Management/Chdi Foundation
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of ATM in human MCF7 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 1 hr by ICW assayMore data for this Ligand-Target Pair