BDBM50551132 CHEMBL4777038
SMILES Cc1ccc(NC(=O)c2ncn(CC(=O)NCCn3ccc4c(N)ncnc34)n2)cc1C
InChI Key InChIKey=RXUMEIKBRRTYMR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50551132
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
University Of Michigan Medical School
Curated by ChEMBL
University Of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of recombinant human DNMT1 using poly(dl-dC) as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Michigan Medical School
Curated by ChEMBL
University Of Michigan Medical School
Curated by ChEMBL
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair