BDBM50551156 CHEMBL4779669

SMILES CS(=O)(=O)N1CCC[C@H](CNc2nonc2\C(Nc2ccc(F)c(Br)c2)=N\O)C1

InChI Key InChIKey=RDYSCDNIOXVFKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551156   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551156(CHEMBL4779669)
Affinity DataIC50: 125nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in N-formylkynurenine production incubated for 12 hrs by microplate reader ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551156(CHEMBL4779669)
Affinity DataIC50: 363nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 30 mins by micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed