BDBM50551206 CHEMBL4761852

SMILES C[C@H](CCC(=O)N[C@H](CC(=O)O)Cc1c[nH]c2ccccc12)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](OC(=O)NC5CCCCC5)CC[C@]4(C)[C@H]3CC[C@]12C

InChI Key InChIKey=PAFZKIGYPITPOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551206   

TargetEphrin type-A receptor 2(Mouse)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551206BDBM50551206(CHEMBL4761852)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50551206BDBM50551206(CHEMBL4761852)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed