BDBM50551276 CHEMBL4759383

SMILES CC[C@H]1N(Cc2ccc(cc2)C(C)(C)C)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCN(C)CC3)ncc2-n2c(C)nnc12

InChI Key InChIKey=YZOJFEPZEVKWPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551276   

TargetSerine/threonine-protein kinase PLK1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50551276(CHEMBL4759383)
Affinity DataIC50: 138nMAssay Description:Inhibition of full length human PLK1 using casein as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50551276(CHEMBL4759383)
Affinity DataIC50: 910nMAssay Description:Inhibition of BRD4 (unknown origin) by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed