BDBM50551302 CHEMBL4791753

SMILES CC[C@H]1N(Cc2cccs2)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCN(C)CC3)ncc2-n2cnnc12

InChI Key InChIKey=QAXLVTMCZJASSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551302   

TargetBromodomain-containing protein 4(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50551302(CHEMBL4791753)
Affinity DataIC50: 73nMAssay Description:Inhibition of BRD4 (unknown origin) by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50551302(CHEMBL4791753)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of full length human PLK1 using casein as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed