BDBM50551638 CHEMBL4790303

SMILES Fc1ccc2[nH]cc(CCCN3CCN(CC(=O)N(C4CCCCC4)c4ccccc4)CC3)c2c1

InChI Key InChIKey=QFHZTAFMZCTOBW-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50551638   

Target5-hydroxytryptamine receptor 1A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50551638(CHEMBL4790303)
Affinity DataEC50:  7nMAssay Description:Agonist activity at recombinant 5HT1A receptor (unknown origin) expressed in CHO cell membrane assessed as [35S]GTPgammaS binding by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50551638(CHEMBL4790303)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human 5H1A receptor expressed in HEK293 cells incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50551638(CHEMBL4790303)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]5-HT from recombinant 5HT1A receptor (unknown origin) expressed in CHO cell membrane measured after 50 mins by microbeta scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50551638(CHEMBL4790303)
Affinity DataKi:  207nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHO-K1 cells measured after 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50551638(CHEMBL4790303)
Affinity DataKi:  2.16E+3nMAssay Description:Antagonist activity at human D2 receptor expressed in HEK293 cells incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed