BDBM50552190 CHEMBL4741714

SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccccc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F

InChI Key InChIKey=GAPPKQMJLOBLDJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50552190   

TargetSerine/threonine-protein kinase pim-1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552190(CHEMBL4741714)
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552190(CHEMBL4741714)
Affinity DataIC50: 0.00900nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552190(CHEMBL4741714)
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of PIM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed