BDBM50552653 CHEMBL4759025

SMILES Clc1ccc(Cn2cncc2C(=O)N2CCN(C3CC3)c3ccccc23)c(Cl)c1

InChI Key InChIKey=FUKYBSBCLLWVBB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552653   

TargetG-protein coupled bile acid receptor 1(Human)
Henan University

Curated by ChEMBL
LigandPNGBDBM50552653(CHEMBL4759025)
Affinity DataEC50:  6.80nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Henan University

Curated by ChEMBL
LigandPNGBDBM50552653(CHEMBL4759025)
Affinity DataEC50:  611nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed