BDBM50552681 CHEMBL4761884

SMILES CNC(=O)c1cnc(Nc2ccc3C(=O)OC(C)(C)c3c2)nc1N[C@H](CO)c1ccccc1

InChI Key InChIKey=BRNMCVNQMQLRHM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50552681   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552681(CHEMBL4761884)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HPK1 (1 to 346 residues) expressed in baculovirus infected Sf9 cells using NH2-fluorescein-RFAR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552681(CHEMBL4761884)
Affinity DataIC50: 47nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552681(CHEMBL4761884)
Affinity DataIC50: 80nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed