BDBM50553219 CHEMBL4742985

SMILES NC(=O)c1cccc(Nc2nc(OCC3CCCCC3)c3nc[nH]c3n2)c1

InChI Key InChIKey=XAOVCENYRWWHPR-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50553219   

TargetCyclin-dependent kinase 2(Human)
Institute of Respiratory Healthand

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553219BDBM50553219(CHEMBL4742985)
Affinity DataIC50: 480nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553219BDBM50553219(CHEMBL4742985)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553219BDBM50553219(CHEMBL4742985)
Affinity DataIC50: 1.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553219BDBM50553219(CHEMBL4742985)
Affinity DataIC50: 1.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMedPDB3D3D Structure (crystal)