BDBM50553426 CHEMBL4746275

SMILES Cc1cc(ccc1CNC(=O)c1cnc(s1)C(C)(C)C)-c1ccnc(Nc2ccncc2)n1

InChI Key InChIKey=MNTGVTWPXKMJCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553426   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553426(CHEMBL4746275)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in BTK phosphorylation measured after 30 mins by phosphotyrosine detection methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553426(CHEMBL4746275)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed