BDBM50553487 CHEMBL4740353

SMILES Nc1nccc(n1)-c1c2cccnc2n2c(N)nccc12

InChI Key InChIKey=JTQQDEMYPLKSDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50553487   

TargetCyclin-dependent kinase 9(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50553487(CHEMBL4740353)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant CDK9 (773 to 928 residues) expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553487(CHEMBL4740353)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CDK9/cyclin T expressed in insect cells using pRB fragment (773 to 928 residues) as substrate incubated for 30 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553487(CHEMBL4740353)
Affinity DataIC50: 210nMAssay Description:Inhibition of human CDK2/cyclin A expressed in insect cells using histone H1 as substrate incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed