BDBM50553885 CHEMBL4745151

SMILES Oc1ccc(cc1F)-n1cc(CNC(=O)c2cc3ccccc3[nH]2)nn1

InChI Key InChIKey=OMRZIIIHHRUMTI-UHFFFAOYSA-N

Data  2 KI  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50553885   

TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553885BDBM50553885(CHEMBL4745151)
Affinity DataKi:  3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553885BDBM50553885(CHEMBL4745151)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553885BDBM50553885(CHEMBL4745151)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF tautomerase activity expressed in Escherichia coli BL21 using 4-hydroxyphenyl pyruvic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553885BDBM50553885(CHEMBL4745151)
Affinity DataKd:  3.63E+3nMAssay Description:Binding affinity to RED-Tris-NTA-labelled C-terminal His-tagged recombinant human MIF tautomerase activity expressed in Escherichia coli BL21 by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553885BDBM50553885(CHEMBL4745151)
Affinity DataKd:  4.40E+3nMAssay Description:Displacement of 4'-(7-Hydroxy-2-oxo-2H-chromen-3-yl)-[1,1'-biphenyl]-4-carboxylic acid from C-terminal His-tagged recombinant human MIF expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553885BDBM50553885(CHEMBL4745151)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF tautomerase activity expressed in Escherichia coli BL21 using 4-hydroxyphenyl pyruvic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553885BDBM50553885(CHEMBL4745151)
Affinity DataIC50: 4.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed