BDBM50553901 CHEMBL4786282

SMILES CC(C)(O)c1coc(c1)S(=O)(=O)NC(=O)Nc1cccc2CCCc12

InChI Key InChIKey=HORCRWKZWUCATI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553901   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553901BDBM50553901(CHEMBL4786282)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome pathway in human THP-1 cells assessed as LPS-stimulated IL-1beta release pretreated with LPS for 3 hrs followed by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553901BDBM50553901(CHEMBL4786282)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed