BDBM50554188 CHEMBL4744686

SMILES COc1cc(OC)c(Cl)c(Nc2ncccc2-c2cc(Nc3c(C)cccc3NC(=O)C=C)ncn2)c1Cl

InChI Key InChIKey=ZQYUWUUBHKOFPC-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554188   

TargetFibroblast growth factor receptor 4(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50554188(CHEMBL4744686)
Affinity DataIC50:  2.93E+3nMAssay Description:Inhibition of N-terminal 6x-His tagged FGFR4 C552A mutant (unknown origin) using IYGEFKKK substrate and [gamma-32P]-ATP incubated for 30 mins by scin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFibroblast growth factor receptor 4(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50554188(CHEMBL4744686)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of N-terminal 6x-His tagged FGFR4 catalytic domain (445-753 residues) (unknown origin) using IYGEFKKK substrate and [gamma-32P]-ATP incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)