BDBM50554356 CHEMBL4758733

SMILES CN(C)c1ccc(Nc2nc(nc3CCC(N)Cc23)-c2ccncc2)cc1

InChI Key InChIKey=CKXSRLUXTFDZCF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554356   

TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554356(CHEMBL4758733)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant wild-type human topoisomerase 2alpha expressed in Saccharomyces cerevisiae using supercoiled pBR322 DNA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554356(CHEMBL4758733)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide dye based ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554356(CHEMBL4758733)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554356(CHEMBL4758733)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant wild-type human topoisomerase 2beta expressed in Saccharomyces cerevisiae using supercoiled pBR322 DNA as substrate measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed