BDBM50554654 CHEMBL4799193

SMILES CC(=O)NC(C(=O)N[C@@H](Cc1c[nH]c2ccccc12)CN(CC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)CN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)CN(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)S(=O)(=O)CC(C)C)S(=O)(=O)c1ccc2ccccc2c1)S(C)(=O)=O)[C@H](C)O

InChI Key InChIKey=WLPCVFPMCVKCCY-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554654   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554654BDBM50554654(CHEMBL4799193)
Affinity DataKd:  83nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554654BDBM50554654(CHEMBL4799193)
Affinity DataKd:  187nMAssay Description:Binding affinity to MDMX (unknown origin) by using FITC-labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed