BDBM50554766 CHEMBL4795492

SMILES CCC(=O)N(Cc1ccccc1)C1(CCN(CCc2ccccc2)CC1)C(=O)NCCc1cccc(F)c1

InChI Key InChIKey=SZQGSEKOXWECKF-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50554766   

TargetDelta-type/Mu-type opioid receptor(Mouse)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  0.0316nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type/Mu-type opioid receptor(Mouse)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  0.0320nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  119nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human MOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  172nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation of [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
St Louis College of Pharmacy and Washington University

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  960nMAssay Description:Agonist activity at EA-fragment beta-arrestin-tagged human DOR expressed in human U2OS cell membranes assessed as stimulation beta-arrestin recruitme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed