BDBM50554823 CHEMBL4745824

SMILES COc1cc2c(c(F)c1N1CCN[C@H](C)C1)n(C(C)C)c1[nH]c3cc(ccc3c1c2=O)C#N

InChI Key InChIKey=IWDGEMCAGXBOIK-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554823   

TargetALK tyrosine kinase receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50554823(CHEMBL4745824)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of N-terminal GST tagged wild-type human ALK cytoplasmic domain (1058-1620 amino acids) expressed Sf9 cells pre-incubated for 30 mins befo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed