BDBM50555344 CHEMBL4757001::US11306078, Example 2.074

SMILES Fc1ccc(-c2cc(no2)C(=O)N[C@H]2CCN(C[C@@H]2C(=O)NC2(CC2)c2ncccn2)C2CCC2)c(F)c1

InChI Key InChIKey=QKLGYSXKZLVSCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50555344   Sort by

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555344(CHEMBL4757001 | US11306078, Example 2.074)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555344(CHEMBL4757001 | US11306078, Example 2.074)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -40 mV holding potential by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555344(CHEMBL4757001 | US11306078, Example 2.074)
Affinity DataIC50: 25nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent