BDBM50555924 CHEMBL4758378

SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(ccc4=O)-c4ccccc4)cc3)ccnc2cc1OCCCCCCC(=O)NO

InChI Key InChIKey=GHRAGOBMSUDFEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50555924   

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50555924(CHEMBL4758378)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of c-MET(unknown origin) using FAM labelled peptide substrate preincubated for 10 mins followed by substrate addition and measured by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50555924(CHEMBL4758378)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50555924(CHEMBL4758378)
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50555924(CHEMBL4758378)
Affinity DataIC50: 18nMAssay Description:Inhibition of human C-terminal Flag tagged HDAC1 (1 to 482 residues) expressed in SF9 cells using Ac-peptide substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed