BDBM50556196 CHEMBL4781948

SMILES CCc1c(C)nc(SCC(=O)Nc2ncc(s2)-c2ccc(OC)cc2)nc1O

InChI Key InChIKey=VJTRWLBHMXKGFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556196   

TargetAnoctamin-1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50556196(CHEMBL4781948)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human ANO1 expressed in FRT cells assessed as inhibition of ATP-induced channel current treated 20 mins prior to ATP challenge and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAnoctamin-1(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50556196(CHEMBL4781948)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human ANO1 channel expressed in HEK293 cells incubated for 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAnoctamin-1(Mouse)
Korea University

Curated by ChEMBL
LigandPNGBDBM50556196(CHEMBL4781948)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of GFP-fused mouse ANO1 channel expressed in HEK293A cells assessed as inhibition of ATP-induced channel current amplitude at membrane pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed