BDBM50556316 CHEMBL4743339

SMILES COc1cccc2nc(Nc3cccc(NC(=O)c4ccc(N5CCOCC5)c(c4)C(F)(F)F)c3)ccc12

InChI Key InChIKey=UJDNEVXCAKHSDH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556316   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50556316(CHEMBL4743339)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of human CRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50556316(CHEMBL4743339)
Affinity DataIC50:  4.57E+3nMAssay Description:Inhibition of human BRAF V600E mutant using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50556316(CHEMBL4743339)
Affinity DataIC50:  4.09E+4nMAssay Description:Inhibition of human BRAF using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed