BDBM50556403 CHEMBL4754192

SMILES O=C(Nc1cc(ccn1)-c1nc(OCC2CC2)c(s1)C(=O)NCCCNc1c2CCCCc2nc2ccccc12)C1CCC1

InChI Key InChIKey=HZTZFAQVGYSTHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556403   

TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50556403(CHEMBL4754192)
Affinity DataIC50: 31nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 1 min followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50556403(CHEMBL4754192)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged GSK-3beta H350L mutant expressed in baculovirus infected Sf21 cells using GSM as substrate inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50556403(CHEMBL4754192)
Affinity DataIC50: 295nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 1 min followed by substrate addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed