BDBM50556643 CHEMBL4786009

SMILES ClC1=C(Nc2ccc(cc2)S(=O)(=O)Nc2ccc(Cl)cn2)C(=O)c2ccccc2C1=O

InChI Key InChIKey=OOPUQETUVRNFID-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556643   

TargetProteasome subunit beta type-5(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556643(CHEMBL4786009)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of chymotrypsin-like activity 20S proteasome beta subunit 5 of human MCF7 cells using fluorogenic substrate Suc-LLVY-AMC after 1 hr by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556643(CHEMBL4786009)
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of trypsin-like activity 20S proteasome beta subunit 2 of human MCF7 cells using fluorogenic substrate Boc-LRR-AMC after 1 hr by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556643(CHEMBL4786009)
Affinity DataIC50: 4.48E+4nMAssay Description:Inhibition of caspase-like activity 20S proteasome beta subunit 1 of human MCF7 cells using fluorogenic substrate Z-LLE-AMC after 1 hr by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed