BDBM50556645 CHEMBL4796470

SMILES [O-][N+](=O)c1ccc(NC(=O)c2ccc(NC3=C(Cl)C(=O)c4ccccc4C3=O)cc2)cc1

InChI Key InChIKey=OSHIKSNZQWLEJY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556645   

TargetProteasome subunit beta type-5(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556645(CHEMBL4796470)
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of chymotrypsin-like activity 20S proteasome beta subunit 5 of human MCF7 cells using fluorogenic substrate Suc-LLVY-AMC after 1 hr by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556645(CHEMBL4796470)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of trypsin-like activity 20S proteasome beta subunit 2 of human MCF7 cells using fluorogenic substrate Boc-LRR-AMC after 1 hr by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Ege University

Curated by ChEMBL
LigandPNGBDBM50556645(CHEMBL4796470)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of caspase-like activity 20S proteasome beta subunit 1 of human MCF7 cells using fluorogenic substrate Z-LLE-AMC after 1 hr by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed