BDBM50556677 CHEMBL4782433

SMILES COc1ccc(C(=O)Nc2c[nH]nc2-c2nc(-c3ccc(CN4CCOCC4)cc3)c[nH]2)cc1

InChI Key InChIKey=TVOOLZURINZODH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50556677   

TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556677BDBM50556677(CHEMBL4782433)
Affinity DataIC50: 14nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556677BDBM50556677(CHEMBL4782433)
Affinity DataIC50: 24nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556677BDBM50556677(CHEMBL4782433)
Affinity DataIC50: 359nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556677BDBM50556677(CHEMBL4782433)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed