BDBM50556678 CHEMBL4744513

SMILES O=C(Nc1c[nH]nc1-c1nc(-c2ccc(CN3CCOCC3)cc2)c[nH]1)c1ccc([N+](=O)[O-])cc1

InChI Key InChIKey=OEWIUKZNWRWPFA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50556678   

TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556678BDBM50556678(CHEMBL4744513)
Affinity DataIC50: 466nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556678BDBM50556678(CHEMBL4744513)
Affinity DataIC50: 569nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556678BDBM50556678(CHEMBL4744513)
Affinity DataIC50: 650nMAssay Description:Inhibition of Aurora B (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556678BDBM50556678(CHEMBL4744513)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed