BDBM50557372 CHEMBL4741221

SMILES CC(C)(C)c1ccc(Cn2cc(nn2)-c2cc(O)c(O)c(O)c2)cc1

InChI Key InChIKey=SBMPGODWJQWUKB-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557372   

TargetHeat shock protein HSP 90-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50557372(CHEMBL4741221)
Affinity DataKd:  63nMAssay Description:Binding affinity to HSP90-alpha (unknown origin) expressed in Escherichia coli BL21 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50557372(CHEMBL4741221)
Affinity DataIC50: 160nMAssay Description:Inhibition of HSP90-alpha (unknown origin) expressed in Escherichia coli BL21 assessed as reduction in ATPase activity in presence of PEP, NADH and A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50557372(CHEMBL4741221)
Affinity DataIC50: 180nMAssay Description:Inhibition of HSP90-beta (unknown origin) expressed in Escherichia coli BL21 assessed as reduction in ATPase activity in presence of PEP, NADH and AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed