BDBM50557540 CHEMBL2420866

SMILES COc1ccc2N(CCCc2c1)c1nc(C)nc2ccccc12

InChI Key InChIKey=SDVCOWGIPMODEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557540   

TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557540(CHEMBL2420866)
Affinity DataIC50: 5nMAssay Description:Inhibition of EGFR in human A431 cells preincubated for 60 mins followed by EGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557540(CHEMBL2420866)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of PDGFRbeta in human SH-SY5Y cells preincubated for 60 mins followed by PDGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50557540(CHEMBL2420866)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of VEGFR2 in human U251 cells preincubated for 60 mins followed by VEGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed